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Laparoscopic and endoscopic cooperative surgery: Is two always better than one?
GI subepithelial tumors (SETs) have traditionally been managed by conventional surgical approaches and nowadays are typically treated by laparoscopic wedge resection. However, precise delineation of the location and margins of SETs can be challenging, thus potentially resulting in removal of additional surrounding healthy tissue to ensure a negative-margin (R0) curative resection.1 On the other hand, endoscopic techniques involving submucosal tunneling and endoscopic resection (STER) can be easily applied only in the proximal stomach, may be inadequate for the complete removal of large SETs involving the deeper wall layers, and are associated with a significant risk of perforation.
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