Fournier坏疽糖尿病患者广泛清创术

                               
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Fournier's gangrene (FG) is a rare but life threatening disease. Although originally thought to be an idiopathic process, FG has been shown to have a predilection for patients with diabetes as well as long term alcohol misuse; however, it can also affect patients with non‐obvious immune compromise.The development and progression of the gangrene is often fulminating and can rapidly cause multiple organ failure and death. Because of potential complications, it is important to diagnose the disease process as early as possible Although antibiotics and aggressive debridement have been broadly accepted as the standard treatment however morbidity and mortality rates are significant.

Fournier's gangrene (FG) is a fulminant form of infective necrotising fascitis of the perineal, genital, or perianal regions, which commonly affects men, but can also occur in women and children. Even though this clinical entity is eponymously credited to the Parisian venerologist Jean‐Alfred Fournier, who described it as a fulminant gangrene of the penis and scrotum in young men, Baurienne in 1764 and Avicenna in 1877 had described the same disease earlier. Over the years, many terms have been used to describe this clinical condition including idiopathic gangrene of the scrotum, periurethral phelgmon, streptococcal scrotal gangrene, phagedena, and synergistic necrotising cellulitis.
Early surgical debridement of necrotic tissues and antibiotics are fundamental in the treatment of FG. Despite advanced management mortality is still high and averages 20%