早期子宫内膜癌的治疗与肥胖病态的回顾性研究比较开放和腹腔镜

早期子宫内膜癌的治疗与肥胖病态的回顾性研究比较开放和腹腔镜
Early endometrial carcinoma therapy in morbid obesity- A retrospective study comparing open and laparoscopic

Abstract
摘要
OBJECT:
对象：
The present study sought to explore the therapeutic outcome of laparoscopic surgery for the endometrial cancer patients with morbidly obese in china.
本研究旨在探讨腹腔镜手术治疗的子宫内膜癌患者的病态肥胖在中国。

METHODS:
方法:
The morbidly obese patients with clinical stage I or II endometrial cancer received laparoscopic surgery (LS) at the Obstetrics and Gynecology centers of PLA general hospital between November 2012 and November 2014. The clinical outcomes of these surgeries were compared with a historical cohort of similar morbidly obese patients who had received the open surgery (OS). In the present study, the morbidly obesity was defined as the body mass index was bigger than 40 kg/m(2). The basic characteristics of the involved patients, the therapeutic effects of the surgery, as well as the incidence of perioperative complications were systematically compared between the two groups.
病态肥胖患者的临床I期或II期子宫内膜癌腹腔镜手术（LS）在解放军总医院2012年十一月和2014年十一月之间的妇产科中心。这些手术的临床结果与类似的病态肥胖患者开腹手术史组进行比较（OS）。在目前的研究中，病态肥胖被定义为体重指数大于40公斤/米（2）。系统比较两组患者所涉及的患者的基本特征、手术的治疗效果，以及围手术期并发症的发生率。

RESULTS:
结果:
Totally 120 patients were included in the present study (respectively 60 patients in the LS group and the OS group). There was no statistical difference between the LS group and the OS group in terms of patient age or BMI. However, the incidence of intraoperative complication in the LS group was significantly lower than that in the OS group (5.0% vs. 16.7%; P = 0.04. Moreover, the incidence of postoperative complication in the OS group was higher than that in the LS group (20.0% vs.6.7%; P = 0.03). The length of hospital stay in the LS group was longer than that in the OS group (6 vs.11 days; P = 0.02). Furthermore, the rates of (pelvic) lymph node dissection and para-aortic node dissection in the LS group were not significantly different from the OS group.
在本研究中，共有120例患者（分别为60例患者在最小二乘组和操作系统组）。在患者的年龄或体重指数方面，在最小二乘组和操作系统组之间无统计学差异。然而，术中并发症的发生率在最小二乘组显着低于在操作系统组（比16.7%，P = 0.04，P = 5%。此外，在OS组术后并发症发生率明显高于LS集团（20% vs.6.7 %；P = 0.03）。在LS组住院时间比OS组延长（6与11天；P = 0.02）。此外，（盆腔）淋巴结清扫和腹主动脉旁淋巴结清扫术组的率没有显着不同，从操作系统组。

CONCLUSION:
结论：
LS is verified to be a safe and rational therapeutic strategy for the endometrial cancer patients with morbidly obese. The incidence of perioperative complications is significantly lower in comparison with the OS.
LS的验证是一种安全、合理，病态肥胖的子宫内膜癌患者的治疗策略。围手术期并发症的发生率显着降低，与操作系统的比较。

原文：
Early endometrial carcinoma therapy in morbid obesity- A retrospective study com.pdf (234.9 KB, 下载次数: 0, 售价: 99 香叶)

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Early endometrial carcinoma therapy in morbid obesity- A retrospective study comparing open and lapa ...