遗传研究子宫内膜异位症的妇女带来了希望！

原文：

Genetic research gives hope for women with endometriosis

Gene research gives hope for women with endometriosis. They identified chromosome 1 and chromosome 7 as being crucial to a women's risk of developing the condition. Dr Krina Zondervan, lead author in the study and research fellow in the University of Oxford, said: There study is really a breakthrough because it supplies the first strong evidence that variations in DNA make some women prone to develop endometriosis.

Endometriosis is a common gynaecological disease which affects around six to 10 percent coming from all women in their reproductive years. Common symptoms include chronic pelvic pain, painful periods along with serious fertility problems in certain women. The situation takes place when cells like those involved with the lining with the womb are located elsewhere within the body. After a women monthly cycle, hormones stimulate the endometriosis, causing it growing, then stop working and bleed. This may lead to inflammation, pain, as well as the formation of adhesions. The best way to diagnose endometriosis is through a process referred to as a laparoscopy which happens under general anaesthetic.

Current treatments are limited by surgery and hormonal drugs which can have side effects. Dr Stephen Kennedy, senior author with the study and head from the Nuffield department of obstetrics and gynaecology at Oxford, said this can now change. We have great confidence the results of this study may help towards developing less invasive ways of diagnosis plus much more effective treating endometriosis. Helen North, from Endometriosis UK, welcomed case study. However, that which you require is to see how this discovery may lead towards effective treatments.

The genomes of 5,500 women with the condition from your UK, US and Australia were than these of 10,000 healthy volunteers. The Nature Genetics study can lead to more potent treatments and diagnosis, researchers said. An endometriosis charity said more research was had to show how this may lead to better treatments.

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子宫内膜异位症基因研究带来了希望。他们发现1号染色体和第7号染色体是非常重要的一个妇女的风险发展的条件。Krina Zondervan，主要作者的研究和牛津大学的研究员，博士说：有研究确实是一个突破，因为它提供的国内第一强有力的证据表明，在DNA的变化使一些妇女容易产生子宫内膜异位症， 子宫内膜异位症是一种常见的妇科所有妇女在生育年龄的疾病，影响约6％至10％。常见的症状包括慢性盆腔疼痛，月经来时疼痛，在某些妇女的生育问题严重。该情况发生时，细胞像那些参与与衬里与子宫位于身体内的其他地方。后女性每月周期，激素刺激子宫内膜异位症，导致它在成长，然后停止工作，并出血。这可能会导致炎症，疼痛，以及形成的粘连。诊断子宫内膜异位症最好的办法是通过一个过程称为一个腹腔镜手术在全身麻醉的情况下， 目前的治疗是有限的外科手术和激素类药物可能有副作用。资深作家斯蒂芬·肯尼迪，在牛津大学纳菲尔德妇产科部门研究和头部，医生说，现在可以改变。我们有很大的信心，这项研究结果可能有助于发展微创的诊断方法，加上更有效的治疗子宫内膜异位症。子宫内膜异位症英国，海伦北，从案例研究表示欢迎。然而，你需要的是怎么看这一发现可能导致对有效的治疗方法。 基因组的5500名妇女的条件从英国，美国和澳大利亚这些为10000名健康的志愿者。“自然遗传学的研究可能会导致更有效的治疗和诊断，研究人员说。的子宫内膜异位症有慈善机构说，更多的研究显示，这可能会导致更好的治疗。