腹腔镜保留神经根治性子宫切除术治疗局部晚期宫颈癌的临床疗效及安全性分析

腹腔镜保留神经根治性子宫切除术治疗局部晚期宫颈癌的临床疗效及安全性分析
Clinical efficacy and safety of laparoscopic nerve-sparing radical hysterectomy for locally advanced cervical cancer

                               
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Abstract
摘要
OBJECTIVE:
目的：
To evaluate the feasibility and safety of laparoscopic nerve-sparing radical hysterectomy (LNRH) for locally advanced cervical cancer (LACC) after neoadjuvant chemotherapy (NACT).
探讨腹腔镜保留神经根治性子宫切除术的可行性和安全性（LNRH）治疗局部晚期宫颈癌（LACC）在新辅助化疗后（NACT）。

METHODS:
方法:
120 patients with stage Ib2 and IIa2 cervical cancer were treated with surgery combined with preoperative NACT in the Department of Obstetrics and Gynecology, PLA General Hospital. Eligible patients were divided into two groups according to surgery type: patients who underwent LNRH were assigned to one group, while the second group included patients who underwent laparoscopic radical hysterectomy (LRH) after administration of NACT. We compared these patients' general clinical information and surgical characteristics, and we assessed their bladder function and intestinal function recovery by questionnaire.
120例Ib2和IIA2宫颈癌患者手术联合术前新辅助化疗治疗产科病区和妇科，解放军总医院。符合条件的患者根据手术方式的不同分为两组：患者接受LNRH被分配到一组，而第二组患者行腹腔镜根治性子宫切除术（LRH）给予NACT后。我们比较了这些患者的一般临床资料和手术特点，并通过问卷调查评估了他们的膀胱功能和肠功能恢复。

RESULTS:
结果:
No significant differences were found between the groups in patients' age or surgical characteristics. The mean duration of postoperative catheterization in the LNRH group was shorter than in the LRH group (P < 0.001). The intestinal and bladder function of patients in the LNRH group also recovered better than that of patients in the LRH group.
在患者的年龄或手术特征组之间没有显著差异。在LNRH组术后导尿管留置时间短于LRH组（P＜0.001）。肠道和膀胱在LNRH组患者功能恢复优于在LRH组患者。

CONCLUSION:
结论：
LNRH is a feasible and safe procedure for LACC after NACT and reduces surgical complications.
LNRH是安全可行的，一般化疗后的程序和减少手术并发症的发生。

原文：
Clinical efficacy and safety of laparoscopic nerve-sparing radical hysterectomy .pdf (259.53 KB, 下载次数: 0, 售价: 99 香叶)

2016-8-26 09:44 上传

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腹腔镜保留神经根治性子宫切除术治疗局部晚期宫颈癌的临床疗效及安全性分析