Next Generation Sequencing in Cancer Research, Volume 2

Next Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides
Springer | Biomedical Sciences | April 25 2015 | ISBN-10: 3319158104 | 493 pages | pdf | 11.4 mb

                               
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by Wei Wu (Editor), Hani Choudhry (Editor)

From the Back Cover
Next Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides, the second in the series “Next Generation Sequencing Technology in Cancer Research―From Basepairs to Bedsides,” is designed to fill the gap between cancer genome research and clinical management of the individual cancer patient. The volume presents the principles of next generation sequencing (NGS) technologies and massively parallel DNA sequencing and their application of the whole genome sequences (WGS), whole exome-seq (WES), RNA-seq, miRNA-seq, and ChIP-seq in cancer research programs and to apply the newly discovered driver genetic alterations for prevention, early diagnosis and genome-oriented precision cancer treatment.

Next Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides brings together the implementation of a wide range of NGS technologies, including single-cell sequencing, in the clinical setting: discovery and validation of cancer biomarkers; standardization of NGS data production; NGS data reporting systems for clinicians; novel anti-cancer therapies development from NGS data; conducting of clinical trials of newly investigated cancer drugs. It provides compelling evidence to signal a new future for health care and a new standard for cancer care.

About the Author
Wei Wu, M.D., Ph.D. is a Research Associate for the Department of Bio Science at the University of Calgary, specializing in the cancer genome and systems biology. He has edited two volumes with Springer. In addition, he's a member of various editorial board for journals including the International Journal of Biomedical Sciences, International Journal of Molecular Medicine and Advances in Sciences and the Research Journal of Biological Sciences.
Hani Choudhry, D.Phil is a member of the Genomics Research Group at the Wellcome Trust Centre for Human Genetics at Oxford University. His expertise is in high throughput next generation sequencing.

Topics
Cancer Research
Human Genetics
Bioinformatics