The Future of HIV-1 Therapeutics

The Future of HIV-1 Therapeutics: Resistance Is Futile?
Springer | Biomedical Sciences | April 22 2015 | ISBN-10: 3319185179 | 254 pages | pdf | 6.75 mb

                               
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by Bruce Torbett (Editor), David S. Goodsell (Editor), Douglas Richman (Editor)

About this book
This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.


Topics
Drug Resistance
Virology
Infectious Diseases