Molecular Pharmacology From DNA to Drug Discovery

Molecular Pharmacology From DNA to Drug Discovery

This edition first published 2013 . 2013 by John Wiley & Sons, Ltd
Wiley-Blackwell is an imprint of John Wiley & Sons, formed by the merger of Wiley’s global Scientific,
Technical and Medical business with Blackwell Publishing.
Registered office: John Wiley & Sons, Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19
8SQ, UK
Editorial offices: 9600 Garsington Road, Oxford, OX4 2DQ, UK
The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK
111 River Street, Hoboken, NJ 07030-5774, USA
For details of our global editorial offices, for customer services and for information about how
to apply for permission to reuse the copyright material in this book please see our website at

The right of the author to be identified as the author of this work has been asserted in accordance with
the UK Copyright, Designs and Patents Act 1988.
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system,
or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or
otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior
permission of the publisher.
Designations used by companies to distinguish their products are often claimed as trademarks. All
brand names and product names used in this book are trade names, service marks, trademarks or
registered trademarks of their respective owners. The publisher is not associated with any product or
vendor mentioned in this book. This publication is designed to provide accurate and authoritative
information in regard to the subject matter covered. It is sold on the understanding that the publisher
is not engaged in rendering professional services. If professional advice or other expert assistance is
required, the services of a competent professional should be sought.
Library of Congress Cataloging-in-Publication Data
Molecular pharmacology : from DNA to drug discovery / John Dickenson . . . [et al.].
p. ; cm.
Includes index.
ISBN 978-0-470-68444-3 (cloth) – ISBN 978-0-470-68443-6 (pbk.)
I. Dickenson, John.
[DNLM: 1. Molecular Targeted Therapy. 2. Pharmacogenetics–methods.
3. Drug Delivery Systems. 4. Drug Discovery. QV 38.5]
615.19–dc23
2012034772
A catalogue record for this book is available from the British Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print
may not be available in electronic books.
Typeset in 9.25/11.5pt Minion by Laserwords Private Limited, Chennai, India.